Hand, Foot and Genital (or Uterus)

Hand, foot and genital (or uterus) syndrome is a condition where the development of the hands, feet, urinary tract and reproductive system is stunted. The thumbs are short, the big toe is short, the feet are short, and there are defects in the ureters. The development of the uterus is abnormal and can increase pregnancy complications later in life. Cause Hand, foot and genital syndrome is a genetic medical condition caused by mutations in the HOXA13 gene. Treatment and Prevention There is no known therapy or preventive measures that doctors know of at the present time. It’s possible that specially designed orthopedic shoes or customized orthotics can help lessen the effects of the faulty anatomical development of the foot.